Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Amfrem2Btlr
Name:	autocrine motility factor receptor; endonuclease-mediated mutation 2, Bruce Beutler
MGI ID:	MGI:6303850
Gene:	Amfr  Location: Chr8:94698216-94739301 bp, - strand  Genetic Position: Chr8, 45.96 cM
Alliance:	Amfrem2Btlr page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated Mutation:    Intragenic deletion   Mutation details: The CRISPR/Cas9 system and sgRNA 5'-TGCTTGCTGTGTTTTGATGT-3' was used to generate the mice. The CRISPR/Cas9 system generated a 7-base pair deletion ATGTTGG at c.453_459del (NM_011787.2). The predicted effect on the protein product was not determined. (J:274568)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Amfr Mutation:	42 strains or lines available

Original:	J:274568 Choi JH, et al., LMBR1L regulates lymphopoiesis through Wnt/beta-catenin signaling. Science. 2019 May 10;364(6440)
All:	1 reference(s)