Tg(Thy1-MFN2)47Balo Transgene Detail MGI Mouse (MGI:6295164)

Tg(Thy1-MFN2)47Balo
Transgene Detail

Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Summary

Symbol:	Tg(Thy1-MFN2)47Balo
Name:	transgene insertion 47, Robert Baloh
MGI ID:	MGI:6295164
Synonyms:	MFN2^WT
Transgene:	Tg(Thy1-MFN2)47Balo Location: unknown
Alliance:	Tg(Thy1-MFN2)47Balo page

Transgene
origin

Strain of Origin:

C57BL/6J

Transgene
description

Transgene Type:

Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)

Mutation:

Insertion

Tg(Thy1-MFN2)47Balo expresses 1 gene

Mutation details: The 9102 bp transgenic construct is designed to contain a murine thymus cell antigen 1, theta (Thy1; Thy1.2) promoter driving expression of a flag-tagged human mitofusin 2 (MFN2) gene. (J:273854)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:273854 Zhou Y, et al., Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model. J Clin Invest. 2019 Mar 18;130:1756-1771
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23