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Gene Expression Data
Assay Details
Assay
Reference: J:26500 Schmitt I, et al., Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development. Hum Mol Genet. 1995 Jul;4(7):1173-82
Assay type: RNA in situ
MGI Accession ID: MGI:6295160
Gene symbol: Htt
Gene name: huntingtin
Probe: Rhd2 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Strong 6d
Specimen 10a/b: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 10a/b Expression restricted to specific seminiferous tubules.
Specimen 10d/e: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 10d/e Elevated expression restricted to distinct stages of spermatogenic differentiation.
TS28: spermatid Ambiguous Regionally restricted 10d/e Authors report pronounced expression is not observed in maturing spermatids in lumen of stage II-VI tubules.
Specimen 10f: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: spermatocyte Strong 10f Strong expression in spermatocytes forming a thick and dense layer within tubules.
TS28: seminiferous tubule epithelium Ambiguous Regionally restricted 10f Authors report pronounced expression is not observed in outer spermatogenic epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory