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Gene Expression Data
Assay Details
Assay
Reference: J:26500 Schmitt I, et al., Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development. Hum Mol Genet. 1995 Jul;4(7):1173-82
Assay type: Northern blot
MGI Accession ID: MGI:6295154
Gene symbol: Htt
Gene name: huntingtin
Probe: Rhd5 probe
Probe preparation: labelled with P32 DNA
Visualized with: Autoradiography
Results Image: 5
 Sample Information Bands Other Sample Information
Lane AgeStructure 13 kb (a) 12 kb 10 kb (a) Amount Genetic BackgroundMutant Allele(s)Sex
brain / ad P adult TS28: brain Strong (b) Present (c) Strong (b) Not Specified; total RNA NMRI Not Specified
head / 18.5 d.p.c. E18.5 TS26: head Strong (b) Present (c) Strong (b) Not Specified; total RNA NMRI Not Specified
liver / 18.5 d.p.c. E18.5 TS26: liver Present Absent Present Not Specified; total RNA NMRI Not Specified
lung / 18.5 d.p.c. E18.5 TS26: lung Present Absent Present Not Specified; total RNA NMRI Not Specified
kidney / 18.5 d.p.c. E18.5 TS26: metanephros Present Absent Present Not Specified; total RNA NMRI Not Specified
heart / 18.5 d.p.c. E18.5 TS26: heart Present Absent Present Not Specified; total RNA NMRI Not Specified
head / 14.5 d.p.c. E14.5 TS22: head Strong (b) Strong (d) Strong (b) Not Specified; total RNA NMRI Not Specified
liver / 14.5 d.p.c. E14.5 TS22: liver Present Absent Present Not Specified; total RNA NMRI Not Specified
lung / 14.5 d.p.c. E14.5 TS22: lung Present Absent Present Not Specified; total RNA NMRI Not Specified
kidney / 14.5 d.p.c. E14.5 TS22: metanephros Present Absent Present Not Specified; total RNA NMRI Not Specified
heart / 14.5 d.p.c. E14.5 TS22: heart Present Absent Present Not Specified; total RNA NMRI Not Specified
placenta / 14.5 d.p.c. E14.5 TS28: placenta Present Absent Present Not Specified; total RNA NMRI Not Specified
Notes:
(a) Authors report expression of 10 kb and 13 kb transcripts in all examined tissues.
(b) Predominant expression in neuronal tissues at all developmental stages.
(c) Authors report an additional transcript of about 12kb in fetal and adult brain.
(d) Predominant expression in brain at E14.5; downregulated at later stages.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory