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Gene Expression Data
Assay Details
Assay
Reference: J:198578 Chervenak AP, et al., Spatiotemporal expression of zic genes during vertebrate inner ear development. Dev Dyn. 2013 Jul;242(7):897-908
Assay type: RNA in situ
MGI Accession ID: MGI:6226135
Gene symbol: Zic4
Gene name: zinc finger protein of the cerebellum 4
Probe: Zic4 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Specimens were postfixed in 4% paraformaldehyde, 0.2% glutaraldehyde.
Results
Specimen 6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst mesenchyme Present Regionally restricted 6E Expression is in the mesenchyme surrounding the epithelium.
TS15: future hindbrain Present Regionally restricted 6E Expression is dorsal.
TS15: otocyst epithelium Absent 6E

Specimen 6K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst mesenchyme Present Regionally restricted 6K Expression is in the mesenchyme surrounding the epithelium.
TS17: hindbrain Present Regionally restricted 6K Expression is dorsal.
TS17: head mesenchyme Present Regionally restricted 6K Expression is adjacent to the dorsolateral side of the otocyst.
TS17: otocyst epithelium Absent 6K

Specimen 6Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear mesenchyme Present Regionally restricted 6Q Expression is in the mesenchyme surrounding the dorsal half of the otic epithelium.
TS19: hindbrain Present Regionally restricted 6Q Expression is dorsal.
TS19: otocyst epithelium Absent 6Q

Specimen 7E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 7E Expression is medially in the mesenchyme between the neural tube and otic epithelium.
TS20: inner ear epithelium Absent 7E

Specimen 7E': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 7E' Expression is medially in the mesenchyme between the neural tube and otic epithelium.
TS20: inner ear epithelium Absent 7E'

Specimen 7K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 7K Expression is medially in the mesenchyme between the neural tube and otic epithelium.
TS21: inner ear epithelium Absent 7K

Specimen 7K': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 7K' Expression is medially in the mesenchyme between the neural tube and otic epithelium.
TS21: inner ear epithelium Absent 7K'

Specimen not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted Expression is dorsal.

Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted Expression is dorsal.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory