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Gene Expression Data
Assay Details
Assay
Reference: J:258232 Wallace J, et al., Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines. Immunology. 2018 Feb;153(2):203-213
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6209821
Gene symbol: Itgam
Gene name: integrin alpha M
Antibody: Anti-CD11b antibody [M1/70] (ab8878)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 2a WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: telencephalon Ambiguous 2a WT merge , 2a WT CD11b Expressed in macrophages/microglia.

Specimen 2a mut: embryonic day 13.5; Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS21: telencephalon Present 2a mut CD11b , 2a mut merge Increased expression in macrophages/microglia.

Specimen 2b WT: postnatal week 11-12 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2b WT merge , 2b WT CD11b Expressed in macrophages/microglia.

Specimen 2b mut: postnatal week 11-12; Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2b mut CD11b , 2b mut merge Increased expression in macrophages/microglia.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory