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Snx1em1Adiuj
Endonuclease-mediated Allele Detail
Summary
Symbol: Snx1em1Adiuj
Name: sorting nexin 1; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID: MGI:6202985
Gene: Snx1  Location: Chr9:65995409-66032168 bp, - strand  Genetic Position: Chr9, 35.71 cM, cytoband D
Alliance: Snx1em1Adiuj page
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
 
Mutation detailsPlasmids encoding a single guide RNA designed to introduce the D465N point mutation into the gene and the cas9 nuclease were introduced into the cytoplasm of fertilized eggs with well recognized pronuclei. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snx1 Mutation:  23 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory