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Gene Expression Data
Assay Details
Assay
Reference: J:145977 Tetreault N, et al., The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation. Dev Biol. 2009 Mar 15;327(2):541-50
Assay type: RNA in situ
MGI Accession ID: MGI:6198687
Gene symbol: Six6
Gene name: sine oculis-related homeobox 6
Probe: Six6 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3C -/-: embryonic day 9.0; Lhx2tm1Dra/Lhx2tm1Dra (more )
Structure Level Pattern Image Note
TS14: optic vesicle neural ectoderm Absent 3C Lhx2-/-

Specimen 3C wt: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: eye neural ectoderm Present Regionally restricted 3C wt Authors state expression spreads to presumptive ventral optic stalk and optic vesicle at E9.0.
TS14: optic vesicle neural ectoderm Present 3C wt

Specimen 3D -/-: embryonic day 9.0; Lhx2tm1Dra/Lhx2tm1Dra (more )
Structure Level Pattern Image Note
TS14: prosencephalon Present Regionally restricted 3D Lhx2-/- Authors report normal expression in prospective pituitary/hypothalamic axis.

Specimen 3D wt: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: prosencephalon Present Regionally restricted 3D wt Expression in prospective pituitary/hypothalamic axis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory