About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:260417 Miesfeld JB, et al., The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody. Gene Expr Patterns. 2018 Jan;27:114-121
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6195191
Gene symbol: Atoh7
Gene name: atonal bHLH transcription factor 7
Reporter: lacZ
Antibody: anti-B-gal
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C: embryonic day 13.5; Atoh7tm1Gla/Atoh7+ (more )
Note: Double labeled: green - Atoh7 reporter; purple - Atoh7 protein (assay MGI:6195177).
Structure Level Pattern Image Note
TS21: retina Present Punctate 2C right , 2C middle In a salt and pepper pattern.
Specimen 2D: embryonic day 13.5; Atoh7tm1Gla/Atoh7tm1Gla (more )
Note: Double labeled: green - Atoh7 reporter; purple - Atoh7 protein (assay MGI:6195177).
Structure Level Pattern Image Note
TS21: retina Present Punctate 2D right , 2D middle In a salt and pepper pattern. Stronger expression than in the heterozygous.
Specimen 5C: embryonic day 13.5; Atoh7tm1Gla/Atoh7+ (more )
Note: Double labeled: green - Atoh7 reporter; purple - Atoh7 protein (assay MGI:6195177).
Structure Level Pattern Image Note
TS21: retina Present Punctate 5C high right , 5C , 5C high middle Atoh7+lacZ-cells (youngest) are restricted to the neuroblast layer, whereas Atoh7-lacZ+ cells (oldest) represent differentiating neurons, e.g. retinal ganglion cells in the ganglion cell layer and cones at the apex. Atoh7+lacZ+ cells (intermediate stage) were mainly located in the neuroblast layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory