Gene Expression Data
Assay Details
Assay
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Reference:
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J:171705
McNeill DS, et al., Development of melanopsin-based irradiance detecting circuitry. Neural Dev. 2011;6:8
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6192525
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Gene symbol:
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Opn4
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Gene name:
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opsin 4 (melanopsin)
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1F E14:
embryonic day 14.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1F E14:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
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Age:
|
embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
1F E15:
embryonic day 15.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1F E15:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Opn4tm1Yau/Opn4+
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Age:
|
embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: neural retina |
Present |
Regionally restricted |
1F E15
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Authors report expression begins at E15. Some expressing cells detected in ganglion cell layer; others appear to be migrating from neuroblast layer to ganglion cell layer.
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Specimen
1G E15:
embryonic day 15.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1G E15:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
embryonic day 15.0
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: neural retina |
Present |
Regionally restricted |
1G E15
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Authors report no expression in peripheral retina at E15.
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Specimen
1G E16:
embryonic day 16.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1G E16:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
embryonic day 16.0
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: neural retina |
Present |
Regionally restricted |
1G E16
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Subsequent expansion of the region of expressing cells.
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Specimen
1G E18:
embryonic day 18.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1G E18:
(close )
Genetic Background:
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involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
1G P0:
postnatal day 0; Opn4tm1Yau/Opn4 +
(more )
Specimen
1G P0:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Opn4tm1Yau/Opn4+
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Age:
|
postnatal day 0
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Sex:
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Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: neural retina |
Present |
Regionally restricted |
1G P0
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Authors report periphery is entirely filled in by P0.
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Specimen
2C P0:
postnatal day 0; Opn4tm1Yau/Opn4 +
(more )
Specimen
2C P0:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: suprachiasmatic nucleus |
Present |
Regionally restricted |
2C P0
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Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
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Specimen
2C P4:
postnatal day 4; Opn4tm1Yau/Opn4 +
(more )
Specimen
2C P4:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 4
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
2C P4
|
Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
|
Specimen
2C P7:
postnatal day 7; Opn4tm1Yau/Opn4 +
(more )
Specimen
2C P7:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 7
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Sex:
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Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
2C P7
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Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
|
Specimen
2C P14:
postnatal day 14; Opn4tm1Yau/Opn4 +
(more )
Specimen
2C P14:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
2C P14
|
Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
|
Specimen
3 E17:
embryonic day 17.0; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 E17:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
embryonic day 17.0
|
Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
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Specimen
3 P1:
postnatal day 1; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P1:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
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Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 1
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P1
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P2:
postnatal day 2; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P2:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 2
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P2
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P3:
postnatal day 3; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P3:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 3
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Sex:
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Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P3
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P4:
postnatal day 4; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P4:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 4
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P4
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P6:
postnatal day 6; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P6:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 6
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P6
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P14:
postnatal day 14; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P14:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P14
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P21:
postnatal day 21; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P21:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 21
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P21
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
3 P49:
postnatal day 49; Opn4tm1Yau/Opn4 +
(more )
Specimen
3 P49:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 49
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: suprachiasmatic nucleus |
Present |
Regionally restricted |
3_P49
|
Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
|
Specimen
4C P0:
postnatal day 0; Opn4tm1Yau/Opn4 +
(more )
Specimen
4C P0:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pretectum |
Absent |
|
4C P0
|
No expression in olivary pretectal nucleus.
|
Specimen
4C P7:
postnatal day 7; Opn4tm1Yau/Opn4 +
(more )
Specimen
4C P7:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 7
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
4C P10:
postnatal day 10; Opn4tm1Yau/Opn4 +
(more )
Specimen
4C P10:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 10
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
4C P14:
postnatal day 14; Opn4tm1Yau/Opn4 +
(more )
Specimen
4C P14:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 14
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
5 P0:
postnatal day 0; Opn4tm1Yau/Opn4 +
(more )
Specimen
5 P0:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
5 P4:
postnatal day 4; Opn4tm1Yau/Opn4 +
(more )
Specimen
5 P4:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 4
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
5 P7:
postnatal day 7; Opn4tm1Yau/Opn4 +
(more )
Specimen
5 P7:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Opn4tm1Yau/Opn4+
|
Age:
|
postnatal day 7
|
Sex:
|
Not Specified
|
Type:
|
section
|
|