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Gene Expression Data
Assay Details
Assay
Reference: J:132390 Alexandrovich A, et al., A role for GATA-6 in vertebrate chondrogenesis. Dev Biol. 2008 Feb 15;314(2):457-70
Assay type: RNA in situ
MGI Accession ID: MGI:6189548
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Probe: Gpr49 probe1
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Present Authors report the major domains of expression were elements of the nervous system and mandibular cleft.
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: thoracic vertebral cartilage condensation Present Regionally restricted 5A Expression domain in thoracic vertebral column broadly overlaps with that of Gata6 and Uncx in centra and pedicle of prevertebra, and head of rib.
TS20: rib pre-cartilage condensation Present Regionally restricted 5A Expression in head of rib.
Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: thoracic vertebral cartilage condensation Present Regionally restricted 5B Expression in prevertebra, particularly in more dorsal elements which will give rise to transverse processes.
TS20: axial skeleton thoracic region Present Regionally restricted 5B No expression in intervertebral discs.
TS20: dorsal root ganglion Absent 5B
Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: radius-ulna pre-cartilage condensation Present Regionally restricted 5C Expression in cartilage primordia of the radius.v
TS20: humerus pre-cartilage condensation Present Regionally restricted 5C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory