Gene Expression Data
Assay Details
Assay
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Reference:
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J:130836
Gerbe F, et al., Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst. Dev Biol. 2008 Jan 15;313(2):594-602
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6189098
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Gene symbol:
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Dab2
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Gene name:
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disabled 2, mitogen-responsive phosphoprotein
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Results
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Specimen
5A:
embryonic day 3.75
(more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Specimen
5A:
(close )
Genetic Background:
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either: CD-1 or ICR
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Age:
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embryonic day 3.75
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
|
Structure |
Level |
Pattern |
Image |
Note |
TS5: blastocyst |
Present |
Regionally restricted |
5A MERGE
,
5A DAB2
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Authors report expression induced in some primitive endoderm cells that have reached the surface, colocalized on the apical side of the cell with Lrp2.
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Specimen
5B:
embryonic day 4.5
(more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Specimen
5B:
(close )
Genetic Background:
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either: CD-1 or ICR
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Age:
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embryonic day 4.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
|
Structure |
Level |
Pattern |
Image |
Note |
TS6: primitive endoderm |
Present |
Regionally restricted |
5B MERGE
,
5B DAB2
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Authors report co-expression with Lrp2 on the apical surface of the primitive endoderm epithelium at E4.5.
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Specimen
5C:
embryonic day 4.5
(more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Specimen
5C:
(close )
Genetic Background:
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either: CD-1 or ICR
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Age:
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embryonic day 4.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
|
Note:
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Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
|
Structure |
Level |
Pattern |
Image |
Note |
TS6: blastocyst |
Present |
Regionally restricted |
5C DAB2
,
5C MERGE
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Authors report co-expression with Lrp2 on the apical surface of the primitive endoderm epithelium at E4.5.
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Specimen
S1B:
embryonic day 3.5
(more )
Note: Double labeled: red - Dab2; green - collagen IV (Col4a1 assay MGI:6189100 or Col4a2 assay MGI:6189097).
Specimen
S1B:
(close )
Genetic Background:
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either: CD-1 or ICR
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Age:
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embryonic day 3.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Dab2; green - collagen IV (Col4a1 assay MGI:6189100 or Col4a2 assay MGI:6189097).
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Structure |
Level |
Pattern |
Image |
Note |
TS4: inner cell mass |
Absent |
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S1B Dab2
,
S1B Merge
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Authors state they were not able to detect expression within the inner cells mass at E3.5, despite strong amplification.
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