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Gene Expression Data
Assay Details
Assay
Reference: J:130836 Gerbe F, et al., Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst. Dev Biol. 2008 Jan 15;313(2):594-602
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6189098
Gene symbol: Dab2
Gene name: disabled 2, mitogen-responsive phosphoprotein
Results
Specimen 5A: embryonic day 3.75 (more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted 5A MERGE , 5A DAB2 Authors report expression induced in some primitive endoderm cells that have reached the surface, colocalized on the apical side of the cell with Lrp2.

Specimen 5B: embryonic day 4.5 (more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Structure Level Pattern Image Note
TS6: primitive endoderm Present Regionally restricted 5B MERGE , 5B DAB2 Authors report co-expression with Lrp2 on the apical surface of the primitive endoderm epithelium at E4.5.

Specimen 5C: embryonic day 4.5 (more )
Note: Double labeled: green - Dab2; red - Lrp2 (assay MGI:6189094).
Structure Level Pattern Image Note
TS6: blastocyst Present Regionally restricted 5C DAB2 , 5C MERGE Authors report co-expression with Lrp2 on the apical surface of the primitive endoderm epithelium at E4.5.

Specimen S1B: embryonic day 3.5 (more )
Note: Double labeled: red - Dab2; green - collagen IV (Col4a1 assay MGI:6189100 or Col4a2 assay MGI:6189097).
Structure Level Pattern Image Note
TS4: inner cell mass Absent S1B Dab2 , S1B Merge Authors state they were not able to detect expression within the inner cells mass at E3.5, despite strong amplification.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory