Lbx1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:251322 Kim M, et al., DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect. Dev Biol. 2017 Nov 15;431(2):297-308
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6163816
Gene symbol:	Lbx1
Gene name:	ladybird homeobox 1

Antibody:	anti-Lbx1
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

4A +/+ ©

Specimen 4A +/+: embryonic day 10.75 (more

)

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4A +/+	Expressed in the muscle progenitors in the hypoglossal cord.
TS18: 1st branchial arch	Present		4A +/+	Expressed in the muscle progenitors.

4A ki/ki ©

Specimen 4A ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4A ki/ki	Expressed in the muscle progenitors in the hypoglossal cord. Significantly decreased number of migratory tongue muscle progenitors compared with the wild-type.
TS18: 1st branchial arch	Present		4A ki/ki	Expressed in the muscle progenitors. Significantly decreased number of migratory tongue muscle progenitors compared with the wild-type.

4B +/+ upper ©

Specimen 4B upper +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4B +/+ upper	Expressed in the muscle progenitors in the hypoglossal cord.

4B ki/ki upper ©

Specimen 4B upper ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4B ki/ki upper	Expressed in the muscle progenitors in the hypoglossal cord.

4B +/+ lower ©

Specimen 4B lower +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: 1st branchial arch	Present		4B +/+ lower	Expressed in the muscle progenitors.

4B ki/ki lower ©

Specimen 4B lower ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: 1st branchial arch	Present		4B ki/ki lower	Expressed in the muscle progenitors.

4C +/+ ©

Specimen 4C +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Dpp9 (assay MGI:6163823).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4C +/+	Expressed in the muscle progenitors in the hypoglossal cord.
TS18: 1st branchial arch	Present		4C +/+	Expressed in the muscle progenitors.

4C ki/ki ©

Specimen 4C ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Dpp9 (assay MGI:6163823).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4C ki/ki	Expressed in the muscle progenitors in the hypoglossal cord.
TS18: 1st branchial arch	Present		4C ki/ki	Expressed in the muscle progenitors.

5A +/+ ©

Specimen 5A +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud mesenchyme	Present		5A +/+	Expressed in muscle progenitors.

5A ki/ki ©

Specimen 5A ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Casp3 (assay MGI:6163821).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud mesenchyme	Present		5A ki/ki	Expressed in muscle progenitors, comparable to the wild-type.

5B ©

Specimen 5B: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Dpp9 (assay MGI:6163823).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud mesenchyme	Present		5B	Expressed in the muscle progenitors.

5C +/+ upper ©

Specimen 5C upper +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Dpp8 (assay MGI:6163824).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud mesenchyme	Present		5C +/+ upper	Expressed in the muscle progenitors.

Specimen 5C upper ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Dpp8 (assay MGI:6163824).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud mesenchyme	Present		5C ki/ki upper	Expressed in the muscle progenitors.

5C +/+ lower ©

Specimen 5C lower +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Dpp8 (assay MGI:6163824).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present		5C +/+ lower	Expressed in the muscle progenitors in the hypoglossal cord.

Specimen 5C lower ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Dpp8 (assay MGI:6163824).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present		5C ki/ki lower	Expressed in the muscle progenitors in the hypoglossal cord.

6A +/+ ©

Specimen 6A +/+: embryonic day 10.75 (more

)
Note: Double labeled: green - Lbx1; red - Cxcr4 (assay MGI:6163828).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	6A +/+	Expressed in the muscle progenitors in the hypoglossal cord.

6A ki/ki ©

Specimen 6A ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: green - Lbx1; red - Cxcr4 (assay MGI:6163828).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	6A ki/ki	Expressed in the muscle progenitors in the hypoglossal cord.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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