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Gene Expression Data
Assay Details
Assay
Reference: J:29762 Bidwell MC, et al., Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation. Endocrinology. 1995 Nov;136(11):5189-201
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6162100
Gene symbol: Pdgfb
Gene name: platelet derived growth factor, B polypeptide
Antibody: anti-PDGF-BB
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Results
Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present Regionally restricted 6A Expressed in the trophoblasts between the spongiotrophoblasts and the decidua.
TS28: decidua Present Regionally restricted 6A Expressed in the trophoblasts between the spongiotrophoblasts and the decidua.
TS20: blood Present Regionally restricted 6A Expressed in the nucleated fetal red blood cells within the insertion of the umbilical vessels at the chorionic plate.
TS20: labyrinthine zone Present 6A
Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present Regionally restricted 6B Expressed in the trophoblasts between the spongiotrophoblasts and the decidua.
TS28: decidua Present Regionally restricted 6B Expressed in the trophoblasts between the spongiotrophoblasts and the decidua.
Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood Strong Regionally restricted 6C Expressed in the nucleated red blood cells of the blood islands.
TS20: labyrinthine zone Moderate 6C Intracellular expression.
TS20: yolk sac visceral endoderm Moderate 6C Intracellular expression.
Specimen 6D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Strong Regionally restricted 6D Expressed in the endothelium of the fetal thoracic aorta.
TS20: blood Strong Regionally restricted 6D Expressed in the nucleated red blood cells.
Specimen 6E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trophoblast giant cell Strong Regionally restricted 6E Expressed in the giant trophoblastic cells located at the periphery of the placenta.
TS20: labyrinthine zone Present 6E
TS20: yolk sac visceral endoderm Present Scattered 6E Sporadic expression.
Specimen 6E uterus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: myometrium Moderate 6E
Specimen 6F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: yolk sac mesenchyme Present Regionally restricted 6F Expressed in the cells within the blood islands.
TS20: yolk sac parietal endoderm Ambiguous 6F Little or no expression.
Specimen 6F uterus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: myometrium Present 6F
TS28: endometrium epithelium Moderate 6F
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: chorionic plate Present Elevated expression.
TS20: blood Present Regionally restricted Elevated expression in the nucleated fetal erythrocytes within the umbilical vessels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory