Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vmn2r1tm2Mom
Name:	vomeronasal 2, receptor 1; targeted mutation 2, Peter Mombaerts
MGI ID:	MGI:6159872
Synonyms:	DeltaC1-GFP
Gene:	Vmn2r1  Location: Chr3:63988968-64016905 bp, + strand  Genetic Position: Chr3, 30.11 cM
Alliance:	Vmn2r1tm2Mom page

Germline Transmission:	Earliest citation of germline transmission: J:262032
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: 230 bp including exon 1 were replaced with a tau-GFP-pA cassette and self-excising ACNF neo selectable marker cassette, resulting in a null allele with GFP reporter. Immunohistochemistry of homozygotes with an antibody recognizing an epitope encoded by exons 3 and 4 failed to detect staining in the vomeronasal organ, proving this a null allele. (J:262032) Inheritance:    Not Specified

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vmn2r1 Mutation:	53 strains or lines available

Original:	J:262032 Akiyoshi S, et al., Subpopulations of vomeronasal sensory neurons with coordinated coexpression of type 2 vomeronasal receptor genes are differentially dependent on Vmn2r1. Eur J Neurosci. 2018 Apr;47(7):887-900
All:	1 reference(s)