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Gene Expression Data
Assay Details
Assay
Reference: J:100569 Sajithlal G, et al., Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme. Dev Biol. 2005 Aug 15;284(2):323-36
Assay type: RNA in situ
MGI Accession ID: MGI:6153547
Gene symbol: Eya1
Gene name: EYA transcriptional coactivator and phosphatase 1
Results
Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: nephrogenic cord caudal part Present Regionally restricted 2A Expression in presumptive nephrogenic mesenchyme - intermediate mesoderm caudal to pronephric and mesonephric anlage.

Specimen 2C: embryonic day 8.5 (more )
Note: Double labeled: blue - Eya1; brown - Lhx1 (assay MGI:6153555).
Structure Level Pattern Image Note
TS13: nephrogenic cord caudal part Present Regionally restricted 2C Expression domain in nephrogenic mesenchyme.

Specimen 2D: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: nephrogenic cord caudal part Present Regionally restricted 2D Expression extends caudally in nephrogenic mesenchyme.

Specimen 2F: embryonic day 9.0 (more )
Note: Double labeled: blue - Eya1; brown - Lhx1 (assay MGI:6153555).
Structure Level Pattern Image Note
TS14: nephrogenic cord caudal part Present Regionally restricted 2F Expression in nephrogenic mesenchyme extends caudally along Wolffian duct laterally.

Specimen 2G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord caudal part Present Widespread 2G Expression throughout entire nephrogenic mesenchyme.

Specimen 2H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord caudal part Strong Regionally restricted 2H Expression stronger in caudal nephrogenic mesenchyme.

Specimen 2I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nephrogenic cord caudal part Present Regionally restricted 2I Expression in nephrogenic mesenchyme anterior to kidney region.
TS17: metanephric mesenchyme Present Regionally restricted 2I Expression in metanephric mesenchyme around ureteric bud.

Specimen 2J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 2J Expression restricted to metanephric mesenchyme
TS19: cap mesenchyme Strong 2J Stronger expression in induced mesenchyme around the ureteric bud.

Specimen not shown: embryonic day 9.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Present Authors report expression levels in nephrogenic cord were similar to wild-type.

Specimen 2K: embryonic day 9.75; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS16: nephrogenic cord caudal part Weak 2K Expression in nephric mesenchyme weaker than in wild-type.

Specimen 2L: embryonic day 10.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Ambiguous 2L uthors state expressing cells in nephric mesenchyme have almost completely disappeared in mutant embryos.
TS17: somite Present 2L

Specimen 5G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present Regionally restricted 5G Expression domain extends substantially anterior.

Specimen 5H: embryonic day 10.5; Gdnftm1Lmgd/Gdnftm1Lmgd (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present Regionally restricted 5H Expression in metanephric mesenchyme similar to that of wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory