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Gene Expression Data
Assay Details
Assay
Reference: J:248338 Teoh JJ, et al., BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain. PLoS One. 2017;12(4):e0175888
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6149055
Gene symbol: Map1b
Gene name: microtubule-associated protein 1B
Antibody: 1B6
Detection system: Secondary antibody
Results
Specimen 6Ai: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Ai
TS25: thalamus Present 6Ai

Specimen 6Aii: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Aii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: thalamus Present 6Aii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen 6Aiii: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Aiii
TS25: thalamus Present 6Aiii

Specimen 6Aiv: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Aiv This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: thalamus Present 6Aiv This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen 6Av: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present 6Av
TS25: neocortex Present 6Av

Specimen 6Avi: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present 6Avi This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: neocortex Present 6Avi This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen S3A ctrl left: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl left Map1b

Specimen S3A ctrl middle: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl middle Map1b

Specimen S3A ctrl right: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl right Map1b

Specimen S3A geo/geo left: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo left Map1b Expression in this mutant is the same as in wild-type.

Specimen S3A geo/geo middle: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo middle Map1b Expression in this mutant is the same as in wild-type.

Specimen S3A geo/geo right: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo right Map1b Expression in this mutant is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory