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Gene Expression Data
Assay Details
Assay
Reference: J:87369 Simon AM, et al., Heart and head defects in mice lacking pairs of connexins. Dev Biol. 2004 Jan 15;265(2):369-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6117711
Gene symbol: Gjc1
Gene name: gap junction protein, gamma 1
Antibody: Connexin 45 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen E10.5 wild-type not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Authors report similar expression in both wild-type and mutant hears at E10.5.
Specimen E10.5 Cx40-/-Cx43-/- not shown: embryonic day 10.5; Gja1tm1Kdr/Gja1tm1Kdr, Gja5tm1Paul/Gja5tm1Paul (more )
Structure Level Pattern Image Note
TS17: heart Present Authors report similar expression in both wild-type and mutant hears at E10.5.
Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart atrium Present 7A
TS20: heart ventricle Present 7A
Specimen 7B: embryonic day 12.5; Gja1tm1Kdr/Gja1tm1Kdr, Gja5tm1Paul/Gja5tm1Paul (more )
Structure Level Pattern Image Note
TS20: heart atrium Present 7B Authors report similar expresion pattern to that of wild-type.
TS20: heart ventricle Present 7B Authors report similar expresion pattern to that of wild-type.
Specimen 7C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ventricle cardiac muscle Present Regionally restricted 7C Authors report punctate as well as diffuse expression.
Specimen 7D: embryonic day 12.5; Gja1tm1Kdr/Gja1tm1Kdr, Gja5tm1Paul/Gja5tm1Paul (more )
Structure Level Pattern Image Note
TS20: ventricle cardiac muscle Present Regionally restricted 7D Authors report punctate as well as diffuse expression.
Specimen 7G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: atrioventricular bundle Present 7G Authors report preferential expression in Purkinje fibers of the His bundle.
TS28: purkinje fiber Present 7G Authors report preferential expression in Purkinje fibers of the His bundle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory