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Gene Expression Data
Assay Details
Assay
Reference: J:87754 Kleinjan DA, et al., Conserved elements in Pax6 intron 7 involved in (auto)regulation and alternative transcription. Dev Biol. 2004 Jan 15;265(2):462-77
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6113931
Gene symbol: Pax6
Gene name: paired box 6
Reporter: lacZ
Direct Detection
Results
Specimen 3B: embryonic day 10.5; Pax6tm1Pgr/Pax6+ (more )
Structure Level Pattern Image Note
TS17: embryo Present 3B

Specimen 4A Pax6 -/-: embryonic day 10.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 4A Pax6 -/- Expression reduced in prosomere 1. Expression maintained in prosomeres 2 and 3.

Specimen 4A Pax6 +/-: embryonic day 10.5; Pax6tm1Pgr/Pax6+ (more )
Structure Level Pattern Image Note
TS17: diencephalon Present 4A Pax6 +/- Expression in all prosomeres (P1, P2 and P3) of diencephalon.

Specimen 4C Pax6 -/-: embryonic day 10.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 4C Pax6 -/- Expression reduced in prosomere 1. Expression maintained in prosomeres 2 and 3.

Specimen 4C Pax6 +/-: embryonic day 10.5; Pax6tm1Pgr/Pax6+ (more )
Structure Level Pattern Image Note
TS17: diencephalon Present 4C Pax6 +/- Expression in all prosomeres (P1, P2 and P3) of diencephalon. Authors report blurring of expression at boundary between prosomere 1 and midbrain.

Specimen 4E Pax6 -/-: embryonic day 11.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS19: prosomere 1 Weak 4E Pax6 -/- Expression reduced in prosomere 1.
TS19: prosomere 2 Present 4E Pax6 -/- Expression maintained in prosomeres 2 and 3.
TS19: prosomere 3 Present 4E Pax6 -/- Expression maintained in prosomeres 2 and 3.

Specimen 4E Pax6 +/-: embryonic day 11.5; Pax6tm1Pgr/Pax6+ (more )
Structure Level Pattern Image Note
TS19: prosomere 1 Present 4E Pax6 +/- Expression in all prosomeres (P1, P2 and P3) of diencephalon.
TS19: prosomere 2 Present 4E Pax6 +/- Expression in all prosomeres (P1, P2 and P3) of diencephalon.
TS19: prosomere 3 Present 4E Pax6 +/- Expression in all prosomeres (P1, P2 and P3) of diencephalon.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory