Gene Expression Data
Assay Details
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Assay
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Reference:
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J:45117
Southard-Smith EM, et al., Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet. 1998 Jan;18(1):60-4
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6095660
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Gene symbol:
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Ednrb
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Gene name:
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endothelin receptor type B
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Probe:
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pWP40
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4a:
embryonic day 10.5
(more  )
Specimen
4a:
(close  )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4b:
embryonic day 10.5; Sox10Dom/Sox10 +
(more )
Specimen
4b:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: migrating neural crest |
Present |
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4b
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There is a developmental delay in the migratory pathway in this mutant compared to wild-type.
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Specimen
4c:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10Dom
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: migrating neural crest |
Present |
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4c
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There is a developmental delay in the migratory pathway in this mutant compared to wild-type.
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Specimen
4d:
embryonic day 11.5
(more )
Specimen
4d:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4e:
embryonic day 11.5; Sox10Dom/Sox10 +
(more )
Specimen
4e:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4f:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10Dom
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4g:
embryonic day 12.5
(more )
Specimen
4g:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
4h:
embryonic day 12.5; Sox10Dom/Sox10 +
(more )
Specimen
4h:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
4i:
(close )
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Genetic Background:
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involves: C3HeB/FeJLe * C57BL/6JLe
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Mutant Allele(s):
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Sox10Dom/Sox10Dom
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Analysis Tools