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Gene Expression Data
Assay Details
Assay
Reference: J:247203 Guo F, et al., ATF6a, a Runx2-activable transcription factor, is a new regulator of chondrocyte hypertrophy. J Cell Sci. 2016 Feb 15;129(4):717-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6094255
Gene symbol: Atf6
Gene name: activating transcription factor 6
Antibody: anti-ATF6
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1Aa: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: bone Absent 1Aa

Specimen 1Ab: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cartilage condensation Present Regionally restricted 1Ab Expression in center and surrounding condensation of cartilage.

Specimen 1Ac: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cartilage condensation Present Regionally restricted 1Ac Expression high in prehypertrophic chondrocytes.

Specimen 1Ad: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: long bone epiphysis Present Regionally restricted 1Ad Expression high in prehypertrophic chondrocytes.

Specimen 1Ae: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: long bone epiphyseal plate hypertrophic zone Present Widespread 1Ae Expression over entire growth plate. Authors report nuclear expression in both proliferating and hypertrophic zones during entire process of chondrogenic development.
TS27: long bone epiphyseal plate proliferative zone Present Widespread 1Ae Expression over entire growth plate. Authors report nuclear expression in both proliferating and hypertrophic zones during entire process of chondrogenic development.

Specimen 1Af: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate hypertrophic zone Present Widespread 1Af Expression over entire growth plate. Authors report nuclear expression in both proliferating and hypertrophic zones during entire process of chondrogenic development.
TS28: long bone epiphyseal plate proliferative zone Present Widespread 1Af Expression over entire growth plate. Authors report nuclear expression in both proliferating and hypertrophic zones during entire process of chondrogenic development.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory