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Wdr72tm1.1Jpsi
Targeted Allele Detail
Summary
Symbol: Wdr72tm1.1Jpsi
Name: WD repeat domain 72; targeted mutation 1.1, James P Simmer
MGI ID: MGI:5913851
Gene: Wdr72  Location: Chr9:74017608-74190485 bp, + strand  Genetic Position: Chr9, 41.06 cM
Alliance: Wdr72tm1.1Jpsi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:242792
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 2 and intron 2 of the gene (153 bp from the translation start site to the end of the exon, plus the first 130 bp of the intron) was replaced with the lacZ reporter gene containing a mouse nuclear localization signal (NLS), and a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination. (J:242792)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wdr72 Mutation:  57 strains or lines available
References
Original:  J:242792 Wang SK, et al., Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation. Mol Genet Genomic Med. 2015 Jul;3(4):302-19
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory