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Gene Expression Data
Assay Details
Assay
Reference: J:18811 Sheppard AM, et al., Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhes Commun. 1994 Apr;2(1):27-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5911109
Gene symbol: Fn1
Gene name: fibronectin 1
Antibody: anti-FN
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 2b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: blood vessel endothelium Present 2b Expression is in the aorta.
TS24: arterial system smooth muscle Present Regionally restricted 2b Expression is in the aorta.
Specimen 2c': embryonic day 15.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS23: blood vessel endothelium Present 2c'
TS23: lung vascular element Present 2c'
TS23: smooth muscle tissue Present 2c'
Specimen 3c': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: esophagus Present Regionally restricted 3c' Expression is on the muscularis smooth muscle layer that surrounds the submucosa.
Specimen 4a': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: heart Present 4a
Specimen 5a': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: liver Present 5a'
Specimen 5c': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: spleen white pulp Present Regionally restricted 5c' Expression is in the sheath surrounding the lymph node.
Specimen 5d': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: spleen Present 5d'
Specimen 5e': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: spleen Present 5e'
Specimen 5f': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: hassall's corpuscle Present 5f'
TS28: thymus epithelium Present Regionally restricted 5f' Expression is in epithelial reticular cells and their desmosomal processes.
Specimen 6b: postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: glomerular mesangium Present 6b
TS28: renal small blood vessel Present 6b
TS28: renal tubule Present 6b
Specimen 7a': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 7a' Expression is in the head mesenchyme surrounding the eye.
Specimen 7d': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: embryo ectoderm Present Single cells 7d' Expression is in migrating melanoblasts.
Specimen 8a': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 8a' Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel Present Regionally restricted 8a' Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell Absent 8a'
Specimen 8b': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 8b' Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel Present Regionally restricted 8b' Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell Absent 8b'
Specimen 8c': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 8c'
Specimen 8d': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present Regionally restricted 8d' Expression is in vessels in the myometrium.
Specimen 9c': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: yolk sac blood vessel Present 9c'
TS21: yolk sac mesenchyme Present 9c'
Specimen not shown E13: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trachea Present Regionally restricted Expression is in the smooth muscle layer.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: aorta endothelium Present
TS28: aorta smooth muscle Present
TS28: blood vessel smooth muscle Present
TS28: small intestine smooth muscle Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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