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Gene Expression Data
Assay Details
Assay
Reference: J:34539 Marvulli D, et al., Spatial and temporal changes of type VI collagen expression during mouse development. Dev Dyn. 1996 Aug;206(4):447-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5906329
Gene symbol: Col6a1
Gene name: collagen, type VI, alpha 1
Antibody: anti-murine type VI collagen (AS-72)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mystacial pad Present Regionally restricted 3A Expression particularly abundant around vibrissae.

Specimen 3B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: skeletal muscle Present Regionally restricted 3B Expression close to the surface of different cell types, like skeletal muscle.

Specimen 3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cornea Strong 3C
TS24: sclera Strong 3C
TS24: conjunctival sac Strong Regionally restricted 3C Strong expression in mesenchyme of conjunctiva.

Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus mesenchyme Present Regionally restricted 3D Expression continuous in mesenchyme surrounding bronchial tree.
TS21: lung mesenchyme Present Regionally restricted 3D In most distal branches, expression detected only at branch point. No expression around newly formed terminal sacs.

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal nerve Present Regionally restricted 3E Expression in peripheral branches of nerves, forming a sheath around axon bundles.

Specimen 3F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 3F Expression in groups of cells in the medulla.

Specimen 3G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nasal mesenchyme Present Regionally restricted 3G Expression close to the surface of different cell types, like nasal epithelia.

Specimen 3H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: oral region mesenchyme Present Regionally restricted 3H Expression close to the surface of different cell types, like oral epithelia.
TS21: tooth mesenchyme Present Regionally restricted 3H In tooth germ, expression more abundant in papilla.

Specimen 3I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: stomach mesenchyme Present Regionally restricted 3I Expression close to the surface of different cell types, like gastric epithelia.

Specimen 4A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intervertebral disc Strong Widespread 4A Strong expression in intervertebral discs, homogeneously distributed throughout the tissue.

Specimen 4C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: elbow joint Strong Regionally restricted 4C Strong expression in articular cartilage.

Specimen PN1: postnatal day 1 (more )
Note: Expression data presented in Table 1.
Structure Level Pattern Image Note
TS27: hair follicle Very strong
TS27: vibrissa Very strong
TS27: genital tubercle Strong
TS27: gonad Strong
TS27: lung Strong
TS27: periosteum Strong
TS27: adrenal gland Present
TS27: brown fat Present
TS27: intervertebral disc Present
TS27: meninges Present
TS27: metanephros Present
TS27: perichondrium Present
TS27: skeletal joint Present
TS27: skeletal muscle Present
TS27: blood vessel Present Regionally restricted Expression in large and small blood vessels.
TS27: dermis Present Regionally restricted Expression in subepidermal mesenchyme.
TS27: alimentary system Present Regionally restricted Expression in digestive tract.
TS27: heart Weak
TS27: liver Weak
TS27: thymus Weak
TS27: tooth Weak
TS27: bone Absent
TS27: central nervous system Absent

Specimen PN12: postnatal day 12 (more )
Note: Expression data presented in Table 1.
Structure Level Pattern Image Note
TS28: gonad Strong
TS28: adrenal gland Present
TS28: heart Present
TS28: liver Present
TS28: lung Present
TS28: dermis Present Regionally restricted Expression in subepidermal mesenchyme.
TS28: alimentary system Present Regionally restricted Expression in digestive tract.
TS28: blood vessel Weak
TS28: intervertebral disc Weak
TS28: metanephros Weak
TS28: skeletal muscle Weak
TS28: thymus Weak
TS28: bone Absent
TS28: central nervous system Absent

Specimen PN60: postnatal day 60 (more )
Note: Expression data presented in Table 1.
Structure Level Pattern Image Note
TS28: adrenal gland Present
TS28: gonad Present
TS28: lung Present
TS28: meninges Present
TS28: dermis Present Regionally restricted Expression in subepidermal mesenchyme.
TS28: blood vessel Weak
TS28: metanephros Weak
TS28: skeletal muscle Weak
TS28: bone Absent
TS28: central nervous system Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory