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Gene Expression Data
Assay Details
Assay
Reference: J:86962 Aruga J, Slitrk6 expression profile in the mouse embryo and its relationship to that of Nlrr3. Gene Expr Patterns. 2003 Dec;3(6):727-33
Assay type: RNA in situ
MGI Accession ID: MGI:5905279
Gene symbol: Lrrn3
Gene name: leucine rich repeat protein 3, neuronal
Results
Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: thalamus Present Regionally restricted 2D Expression in ventrolateral part of dorsal thalamus. Strong expression in thalamic eminence.`
TS21: cerebral cortex Weak 2D
TS21: olfactory lobe Weak Regionally restricted 2D Weak expression in piriform cortex.
TS21: forebrain-midbrain boundary region Weak Regionally restricted 2D Weak expression in pretectum.

Specimen 2H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: thalamus Present Regionally restricted 2H Authors report expression more broadly in thalamus, but weak or absent in Slitrk6-expressing regions.

Specimen 2J: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: thalamus Present Regionally restricted 2J

Specimen 2L: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: lateral habenular nucleus Present 2L
TS28: medial habenular nucleus Present 2L

Specimen 3B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pons ventricular layer Present 3B Expression in pontine neuroepithelium (ventricular layer).

Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebellum Strong Regionally restricted 3D Strong expression in rostral and caudal regions. Expression densely distributed in deeper layer where Purkinje cell precursors are known to be located.
TS23: cerebellum external granule cell layer Absent 3D No expression in external germinal layer, where granule neurons precursors are clustered.

Specimen 4B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: head Ambiguous 4B

Specimen 4F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cochlear ganglion Present 4F Expression in cochlear spiral ganglion cells which form synapses with hair cells.

Specimen 4H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina layer Trace Regionally restricted 4H Very weak expression in retinal ganglion cell layer.

Specimen 4J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vibrissa Weak Regionally restricted 4J Weak expression in layer surrounding area expressing Slitrk6.

Specimen 4L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nasal epithelium Present Regionally restricted 4L Dense expression in posterior part of nasal epithelium.

Specimen 4N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue epithelium Present Regionally restricted 4N Expression in lateral surface of tongue, adjacent to region showing Slitrk6 expression.
TS21: upper jaw molar mesenchyme Present Regionally restricted 4N Expression in mesenchyme surrounding invaginating oral epithelium forming upper molar teeth primordia.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory