About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:69393 Naruse-Nakajima C, et al., Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mech Dev. 2001 Apr;102(1-2):95-105
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5903468
Gene symbol: Epha2
Gene name: Eph receptor A2
Reporter: lacZ
Direct Detection
Results
Specimen 2B: postnatal day 10; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS28: tail vertebra Present Regionally restricted 2B Expression in hypotrophic chondrocytes in ectopic vertebra.

Specimen 2C: postnatal day 10; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS28: tail vertebra Present Regionally restricted 2C Expression in hypotrophic chondrocytes in ectopic vertebra.

Specimen 7.5 dpc not shown: embryonic day 7.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS11: node Present

Specimen 8.5 dpc not shown: embryonic day 8.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS13: node Present Expression at node from 7.5 through 9.5 dpc.
TS13: rhombomere 4 Present Expression at rhombomere 4 between 8.5 and 9.5 dpc.

Specimen 4A: embryonic day 9.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS15: tail Present Regionally restricted 4A Authors report expression at node from 7.5 through 9.5 dpc.
TS15: rhombomere 4 Present 4A Expression at rhombomere 4 between 8.5 and 9.5 dpc.
TS15: caudal neuropore Present 4A Expression at posterior neuropore at 9.5 dpc.
TS15: notochord Present Regionally restricted 4A Expression at tip of tail notochord from 9.5 through 12.5 dpc.

Specimen 4B: embryonic day 10.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS17: notochord Present Regionally restricted 4B Expression at tip of tail notochord from 9.5 through 12.5 dpc.

Specimen 4C: embryonic day 10.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS17: tail Present Regionally restricted 4C Authors report expression in homozygote mutant tail indistinguishable from that of heterozygotes until 10.5 dpc.

Specimen 4D: embryonic day 11.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS19: notochord Present Punctate 4D Expression at tip of tail notochord from 9.5 through 12.5 dpc.

Specimen 4E: embryonic day 11.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS19: notochord Present 4E Expression in cells spreading more broadly and extending into more caudal region,

Specimen 4F: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS20: limb Present 4F
TS20: lung Present 4F
TS20: nose Present 4F
TS20: notochord Present Regionally restricted 4F Expression in cells spreading more broadly and extending into more caudal region,

Specimen 4G: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: limb Present 4G
TS20: lung Present 4G
TS20: nose Present 4G

Specimen 4H: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 4H Expression at tip of tail notochord from 9.5 through 12.5 dpc.

Specimen 4I: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 4I Expression concentrated at two points.

Specimen adult not shown: postnatal adult; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS28: intestine Present
TS28: liver Present
TS28: lung Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory