Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:69393
Naruse-Nakajima C, et al., Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mech Dev. 2001 Apr;102(1-2):95-105
|
Assay type:
|
In situ reporter (knock in)
|
MGI Accession ID:
|
MGI:5903468
|
Gene symbol:
|
Epha2
|
Gene name:
|
Eph receptor A2
|
Reporter:
|
lacZ
|
|
Direct Detection
|
|
Results
|
Specimen
2B:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS28: tail vertebra |
Present |
Regionally restricted |
2B
|
Expression in hypotrophic chondrocytes in ectopic vertebra.
|
Specimen
2C:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS28: tail vertebra |
Present |
Regionally restricted |
2C
|
Expression in hypotrophic chondrocytes in ectopic vertebra.
|
Specimen
7.5 dpc not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: node |
Present |
|
|
|
Specimen
8.5 dpc not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: node |
Present |
|
|
Expression at node from 7.5 through 9.5 dpc.
|
TS13: rhombomere 4 |
Present |
|
|
Expression at rhombomere 4 between 8.5 and 9.5 dpc.
|
Specimen
4A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: tail |
Present |
Regionally restricted |
4A
|
Authors report expression at node from 7.5 through 9.5 dpc.
|
TS15: rhombomere 4 |
Present |
|
4A
|
Expression at rhombomere 4 between 8.5 and 9.5 dpc.
|
TS15: caudal neuropore |
Present |
|
4A
|
Expression at posterior neuropore at 9.5 dpc.
|
TS15: notochord |
Present |
Regionally restricted |
4A
|
Expression at tip of tail notochord from 9.5 through 12.5 dpc.
|
Specimen
4B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: notochord |
Present |
Regionally restricted |
4B
|
Expression at tip of tail notochord from 9.5 through 12.5 dpc.
|
Specimen
4C:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail |
Present |
Regionally restricted |
4C
|
Authors report expression in homozygote mutant tail indistinguishable from that of heterozygotes until 10.5 dpc.
|
Specimen
4D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: notochord |
Present |
Punctate |
4D
|
Expression at tip of tail notochord from 9.5 through 12.5 dpc.
|
Specimen
4E:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS19: notochord |
Present |
|
4E
|
Expression in cells spreading more broadly and extending into more caudal region,
|
Specimen
4F:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Specimen
4G:
(close )
Specimen
4H:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Formaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: notochord |
Present |
Regionally restricted |
4H
|
Expression at tip of tail notochord from 9.5 through 12.5 dpc.
|
Specimen
4I:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS20: notochord |
Present |
Regionally restricted |
4I
|
Expression concentrated at two points.
|
Specimen
adult not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
Mutant Allele(s):
|
Epha2Gt(ROSABetageo)CN3Yiw/Epha2+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Fixation:
|
Formaldehyde
|
|