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Mahl129S1/SvImJ
QTL Variant Detail
Summary
QTL variant: Mahl129S1/SvImJ
Name: modifier of age related hearing loss; 129S1/SvImJ
MGI ID: MGI:5898321
QTL: Mahl  Location: unknown  Genetic Position: Chr10, Syntenic
Variant
origin
Strain of Specimen:  129S1/SvImJ
Variant
description
Allele Type:    QTL
Mutation:    Undefined
 
Mutation detailsIn the homozygous state this allele intensifies the hair cell loss and hearing loss caused by the age related hearing loss mutation on the 129S1 background (J:241137)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
References
Original:  J:241137 Johnson KR, et al., Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains. Sci Rep. 2017 Mar 13;7:44450
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory