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Gene Expression Data
Assay Details
Assay
Reference: J:165710 Brown GD, et al., Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-beta3. BMC Dev Biol. 2010;10:93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5883326
Gene symbol: Mmp25
Gene name: matrix metallopeptidase 25
Antibody: MMP-25 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2A/E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf epithelium Strong 2A/E Expression appears stronger in palate shelf epithelium than in the underlying mesenchyme. Strongest expression in epithelium of palate shelves.
TS20: palatal shelf mesenchyme Present Regionally restricted 2A/E Expression also visible in apical mesenchyme.
Specimen 2B/F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Strong 2B/F Expression appears stronger in palate shelf epithelium than in the underlying mesenchyme. Strongest expression in epithelium of palate shelves.
TS21: palatal shelf mesenchyme Present Regionally restricted 2B/F Expression also visible in apical mesenchyme.
Specimen 2C/G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Strong 2C/G
TS22: palatal shelf mesenchyme Present Regionally restricted 2C/G Expression also visible in apical mesenchyme.
Specimen 2D/H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: palatal shelf epithelium Present Regionally restricted 2D/H Expression weaker in degrading epithelium between palate shelves. Prominent expression in oral epithelium and remnant of the midline epithelial seam (MES).
TS23: palatal shelf mesenchyme Present 2D/H
Specimen 7C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart Present 7C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory