About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:238674 Barrett NA, et al., Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016 Jul 26;16(4):1039-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5824575
Gene symbol: Kmt2a
Gene name: lysine (K)-specific methyltransferase 2A
Results
Specimen 1C: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS19: nephric duct, mesonephric portion Present Regionally restricted 1C Expression in mesonephric ducts.
TS19: urogenital ridge Present Regionally restricted 1C Expression in the tips of the urogenital ridges.
Specimen 1C inset: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 1C inset Expression in circulating hematopoietic cells (HC) in the aortic lumen.
TS19: trunk mesenchyme Present Regionally restricted 1C inset Expression in sub-aortic mesenchymal cells.
TS19: sympathetic nervous system Present 1C inset
Specimen 1D: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 1D (merge) , 1D Mll1 Expression in circulating hematopoietic cells (HC) in the aortic lumen.
TS19: trunk mesenchyme Present Regionally restricted 1D (merge) , 1D Mll1 Expression in sub-aortic mesenchymal cells.
TS19: dorsal aorta Present Regionally restricted 1D Mll1 , 1D (merge) Expression in intra-aortic cluster cells.
Specimen 1E: embryonic day 11.5 (more )
Note: Multi-labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted 1E (merge) , 1E Mll1 Expression in intra-aortic cluster cells.
Specimen 1F: embryonic day 14.5 (more )
Note: Multi-labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS22: liver Present 1F (merge) , 1F Mll1
Specimen 1G: embryonic day 12.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS20: chorioallantoic placenta Present Widespread 1G Authors report widespread expression, with cells in and around the major vessels, including the umbilical artery.
TS20: umbilical artery Present 1G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory