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Gene Expression Data
Assay Details
Assay
Reference: J:124347 Heinzel K, et al., The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis. Eur J Immunol. 2007 Sep;37(9):2562-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5824281
Gene symbol: Cd8a
Gene name: CD8 subunit alpha
Antibody: anti-CD8a
Results
Specimen 4B dKO: postnatal week 4-6; Pcolce2tm1Ccb/Pcolce2tm1Ccb, Ppp1r16btm1Ccb/Ppp1r16btm1Ccb (more )
Note: Triple labeled: red - Cd8a; green - Cd4 (assay MGI:5824280); blue - B220 (Ptprc assay MGI:5824282).
Structure Level Pattern Image Note
TS28: thymus Present Regionally restricted 4B dKO merge (lower) , 4B dKO CD8 Authors report stromal and lymphoid cells located in correct thymic niches.
Specimen 4B WT: postnatal week 4-6 (more )
Note: Triple labeled: red - Cd8a; green - Cd4 (assay MGI:5824280); blue - B220 (Ptprc assay MGI:5824282).
Structure Level Pattern Image Note
TS28: thymus Present Regionally restricted 4B WT merge (lower) , 4B WT CD8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory