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Gene Expression Data
Assay Details
Assay
Reference: J:62068 Hjalt TA, et al., The Pitx2 protein in mouse development. Dev Dyn. 2000 May;218(1):195-200
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5823861
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Antibody: P2R10
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2A/E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: perioptic mesenchyme Present 2A/E

Specimen 2B/F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cornea epithelium Strong 2B/F
TS21: cornea stroma Strong 2B/F
TS21: extrinsic ocular pre-muscle mass Strong 2B/F
TS21: perioptic mesenchyme Weak 2B/F
TS21: lens Absent 2B/F
TS21: neural retina Absent 2B/F
TS21: optic stalk Absent 2B/F No expression in the neural layer of the optic stalk.

Specimen 2C/G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: eye anterior segment Strong Regionally restricted 2C/G Stronger expression in iris.
TS23: cornea epithelium Weak 2C/G
TS23: cornea stroma Weak 2C/G

Specimen 2D/H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: iris Present 2D/H Expression reduced everywhere except the iris.

Specimen 2I/L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar dental lamina Present 2I/L
TS21: upper jaw molar epithelium Present 2I/L
TS21: upper jaw molar mesenchyme Absent 2I/L

Specimen 2J/M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw incisor enamel organ Present 2J/M
TS23: upper jaw incisor enamel organ Present 2J/M

Specimen 2K/N: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor dental lamina Present 2K/N
TS26: lower jaw incisor enamel organ Present 2K/N

Specimen 3A/F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart atrium Present Regionally restricted 3A/F Expression in wall of left atrium.

Specimen 3B/G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: left atrium Present Regionally restricted 3B/G Expression in wall of left atrium.
TS19: septum primum Present 3B/G

Specimen 3C/H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: left atrium Present Regionally restricted 3C/H Expression in walls of left and right atria.
TS20: right atrium Present Regionally restricted 3C/H Expression in walls of left and right atria.
TS20: septum primum Present 3C/H
TS20: endocardial cushion Absent 3C/H

Specimen 3D/I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: gut Present Regionally restricted 3D/I Expression in left wall of gut tube.
TS15: left vitelline vein Present Regionally restricted 3D/I Expression in wall of left vitelline vein.

Specimen 3E/J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: midgut Present 3E/J

Specimen 4A/F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 4A/F

Specimen 4B/G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pituitary gland Present 4B/G

Specimen 4C/H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: umbilical artery Present Regionally restricted 4C/H Expression in walls of veins and arteries in the umbilical region.
TS19: umbilical vein Present Regionally restricted 4C/H Expression in walls of veins and arteries in the umbilical region.

Specimen 4D/I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: umbilical artery Present Regionally restricted 4D/I Expression in walls of veins and arteries in the umbilical region.
TS26: umbilical vein Present Regionally restricted 4D/I Expression in walls of veins and arteries in the umbilical region.

Specimen 4E/J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: left lung mesenchyme Present 4E/J

Specimen 4K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: umbilical blood vessel Present Regionally restricted 4K Authors report nuclear localization of expression in the umbilicus.

Specimen 4L: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: incisor Present Regionally restricted 4L Authors report nuclear localization of expression in the umbilicus.

Specimen E9.5 not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: umbilical artery Present Regionally restricted Expression in walls of veins and arteries in umbilical region.
TS15: umbilical vein Present Regionally restricted Expression in walls of veins and arteries in umbilical region.
TS15: hindlimb ridge Present Authors report expression in hindlimb buds.

Specimen E12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: common dorsal aorta Weak Regionally restricted Weak expression in wall of descending thoracic aorta.
TS20: posterior cardinal vein Weak Regionally restricted Weak expression in left posterior cardinal vein.
TS20: umbilical blood vessel Present Regionally restricted Authors report nuclear localization of expression in the umbilicus.

Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: meninges Present Regionally restricted Authors report expression in mesenchyme of outer table of primitive ectomeninx.

Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Absent
TS22: lung Absent
TS22: trunk musculature Present Regionally restricted Expression in cutaneous muscles of the trunk.
TS22: intercostal muscle Present
TS22: eye Present Regionally restricted Authors report nuclear localization of expression in the eye.

Specimen E15.5 not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal mesenchyme Present Regionally restricted Expression in mesenchyme adjacent to nasal structures.
TS23: diencephalon Present


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory