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Gene Expression Data
Assay Details
Assay
Reference: J:203593 Kim HG, et al., Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. Am J Hum Genet. 2012 Jul 13;91(1):56-72
Assay type: RNA in situ
MGI Accession ID: MGI:5822838
Gene symbol: Phf21a
Gene name: PHD finger protein 21A
Probe: Phf21a cDNA1
Probe preparation: Antisense labelled with S35 RNA
Assay notes: Three different Phf21a antisense probes gave consistent results.
Results
Specimen 4F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4F Expressed in the roof (ventricular) region.
TS21: neocortex Present Regionally restricted 4F Expressed in the roof (ventricular) region.
TS21: cerebral cortex ventricular layer Present 4F
TS21: midbrain ventricular layer Present 4F
TS21: spinal cord Present 4F
Specimen 4G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metencephalon Present Regionally restricted 4G Expressed in the intraventricular portion of the cerebellar primordium.
TS22: cerebral cortex ventricular layer Present 4G
TS22: midbrain ventricular layer Present 4G
TS22: spinal cord Present 4G
Specimen 4H/I: embryonic day 17.5 (more )
Note: Signals in the intestine in H were also detected with the sense probes and are most likely not specific (these are marked by asterisks).
Structure Level Pattern Image Note
TS25: viscerocranium bone Strong Regionally restricted 4I , 4H Expressed in the palatine bone.
TS25: orbito-sphenoid Strong 4H , 4I
TS25: chondrocranium Strong 4I , 4H
Specimen 4J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 4J Expressed in the neuronal layers.
TS28: cerebellum granule cell layer Present 4J
TS28: main olfactory bulb Present 4J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory