Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mir96tm2.2Wtsi
Name:	microRNA 96; targeted mutation 2.2, Wellcome Trust Sanger Institute
MGI ID:	MGI:5817459
Gene:	Mir96  Location: Chr6:30169445-30169550 bp, - strand  Genetic Position: Chr6, 12.52 cM
Alliance:	Mir96tm2.2Wtsi page
IMPC:	Mir96 gene page

Germline Transmission:	Earliest citation of germline transmission: J:174268
Parent Cell Line:	JM8A3 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	IMPC

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion of Chromosome 6 (Genome Build 37). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and finally an FRT site. Recombination events removed the selection cassette.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir96 Mutation:	6 strains or lines available

Original:	J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5
All:	2 reference(s)