Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Trem2em3Adiuj
Name:	triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 3, MODEL-AD Center
MGI ID:	MGI:5816607
Synonyms:	Trem2 Y38C KI
Gene:	Trem2  Location: Chr17:48653429-48659304 bp, + strand  Genetic Position: Chr17, 23.99 cM, cytoband C
Alliance:	Trem2em3Adiuj page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Humanized sequence) Mutations:    Insertion, Nucleotide substitutions   Mutation details: The allele was generated by injecting cas9 nuclease and a single guide RNA designed to introduce a Y38C point mutation into the gene. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trem2 Mutation:	65 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)