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Pkn1tm1.1Dwu
Targeted Allele Detail
Summary
Symbol: Pkn1tm1.1Dwu
Name: protein kinase N1; targeted mutation 1.1, Dianqing Wu
MGI ID: MGI:5811753
Gene: Pkn1  Location: Chr8:84393165-84425808 bp, - strand  Genetic Position: Chr8, 40.22 cM
Alliance: Pkn1tm1.1Dwu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector is designed to insert a loxP site upstream of exon 13 and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 22, which includes the STOP codon. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 13 through 22 floxed. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pkn1 Mutation:  45 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory