Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	L3mbtl2tm1.1Haho
Name:	L3MBTL2 polycomb repressive complex 1 subunit; targeted mutation 1.1, Hanno Hock
MGI ID:	MGI:5810649
Synonyms:	FLdeltaN
Gene:	L3mbtl2  Location: Chr15:81548090-81572516 bp, + strand  Genetic Position: Chr15, 38.19 cM
Alliance:	L3mbtl2tm1.1Haho page

Germline Transmission:	Earliest citation of germline transmission: J:227373
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites flanking exons 9-14 and a neomycin gene flanked by FRT sites were inserted via homologous recombination. Flp-mediated recombination removed the neomycin gene. (J:227373)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any L3mbtl2 Mutation:	53 strains or lines available

Original:	J:227373 Qin J, et al., The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell. 2012 Sep 7;11(3):319-32
All:	2 reference(s)