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Gene Expression Data
Assay Details
Assay
Reference: J:124995 Etournay R, et al., Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. J Cell Sci. 2007 Aug 15;120(Pt 16):2838-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5806145
Gene symbol: Shroom2
Gene name: shroom family member 2
Results
Specimen 3A: embryonic day 15.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS23: olfactory epithelium Present 3A +ZO1 , 3A mShrm2
Specimen 3B: embryonic day 15.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS23: choroid plexus Present 3B mShrm2 , 3B merge
Specimen 3C: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: stomach glandular epithelium Present Regionally restricted 3C +ZO1 , 3C mShrm2 Expression is at the tight junctions and at the most apical border of cell-cell contacts.
Specimen 3D: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Ctnnb1 (assay MGI:5806146).
Structure Level Pattern Image Note
TS28: stomach glandular epithelium Present Regionally restricted 3D mShrm2 , 3D +beta-catenin Expression is at the tight junctions and at the most apical border of cell-cell contacts.
Specimen 3E: postnatal day 20 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 3E merge , 3E mShrm2 Expression is at the tight junctions and at the most apical border of cell-cell contacts.
Specimen 3F: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 3F +Ecadherin , 3F mShrm2 Expression is at the tight junctions and at the most apical border of cell-cell contacts.
Specimen 4A: embryonic day 14.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Strong 4A
Specimen 4B: embryonic day 14.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Strong 4B merge , 4B mShrm2
Specimen 4C: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present 4C Expression is concentrated at the tight junctions.
TS28: retina inner plexiform layer Present Regionally restricted 4C Expression is in neuronal extensions.
Specimen 4D: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present 4D mShrm2 , 4D merge Expression is concentrated at the tight junctions.
Specimen 4E: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present 4E YZ top , 4E mShrm2 + ZO1 Expression is concentrated at the tight junctions.
Specimen 5A: embryonic day 12.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS20: cochlear duct epithelium Very strong Regionally restricted 5A +ZO1 , 5A mShrm2 Expression is at the apical surface.
Specimen 5B: embryonic day 16.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS24: organ of Corti Very strong Regionally restricted 5B mShrm2 , 5B +ZO1 Expression is in the sensory epithelium.
Specimen 5C: postnatal day 2 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS27: organ of Corti Strong Regionally restricted 5C mShrm2 , 5C +ZO1 There is diffuse labeling throughout the cytoplasm of the sensory inner and outer hair cells and pillar cells.
Specimen 5D: postnatal day 10 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: organ of Corti Strong Regionally restricted 5D +ZO1 , 5D mShrm2 Expression is at the tightly joined apical domains of the hair cells and their adjacent supporting cells, forming the reticular lamina.
Specimen 5E: postnatal day 14 (more )
Note: Double labeled: green - Shroom2; red - F-actin.
Structure Level Pattern Image Note
TS28: stria vascularis Strong Regionally restricted 5E+ F-actin , 5E mShrm2 Expression is at the apical cell-cell junctions of the marginal cells and is stronger at the tricellular contacts.
Specimen 5F: postnatal day 2 (more )
Note: Double labeled: green - Shroom2; red - Myo7a (assay MGI:5806148).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 5F
Specimen S3A: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted S3A + ZO1 , S3A mShrm2 Expression is in the apical region of the epithelia.
Specimen S3B: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: submandibular gland Present Regionally restricted S3B mShrm2 , S3B + ZO1 Expression is in the apical region of the epithelia.
Specimen S3C: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: intestine epithelium Present S3C 3 , S3C 2 , S3C , S3C 1 Expression is in the apical region.
Specimen S3C right: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestine epithelium Present Regionally restricted S3C right Expression is in the apical region.
Specimen S3D Gastric gland: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: stomach glandular epithelium Present S3D Gastric gland Expression is in the apical region.
Specimen S3D Kidney: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: metanephros epithelium Present S3D Kidney Expression is in the apical region.
Specimen S3D Lung: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: lung epithelium Present S3D Lung Expression is in the apical region.
Specimen S3D Liver: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: liver Present S3D Liver Expression is in the apical region of the epithelia.
Specimen S3D Intestine: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Cdh1 (assay MGI:5806147).
Structure Level Pattern Image Note
TS28: intestine epithelium Present Regionally restricted S3D Intestine Expression is in the apical region.
Specimen S3E: postnatal adult (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: choroid plexus epithelium Present S3E + mShrm2 Expression is in the apical region.
Specimen S3F Forebrain: postnatal adult (more )
Structure Level Pattern Image Note
TS28: forebrain Present Regionally restricted S3F Forebrain Expression is in some axons of neurons.
Specimen S3F Hindbrain: postnatal adult (more )
Structure Level Pattern Image Note
TS28: 4th ventricle ependyma Present S3F Hindbrain Expression is in the apical region.
TS28: capillary Present Regionally restricted S3F Hindbrain Expression is in brain capillaries.
Specimen S3F Cerebellum: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted S3F Cerebellum Expression is in some axons.
Specimen S3G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present Regionally restricted S3G right , S3G left Expression is in the head.
Specimen S3H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: metanephros epithelium Present Regionally restricted S3H right , S3H left Most of the expression is at the luminal apical surface and some is localized to the tight junctions.
Specimen S4E: embryonic day 14.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present S4E mShrm2 , S4E mShrm2 + ZO1 Expression is concentrated at the tight junctions.
TS22: neural retinal epithelium Present Regionally restricted S4E mShrm2 + ZO1 , S4E mShrm2 Expression is in some neuronal processes in the inner region of the neuroretina.
Specimen S4F: embryonic day 14.0 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present S4F mShrm2 , S4F mShrm2 + ZO1 Expression is concentrated at the tight junctions.
Specimen S5A cochlear ganglion: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present Regionally restricted S5A cochlear ganglion Expression is along the neuronal processes of neurons.
Specimen S5A stria vascularis: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: stria vascularis Present Regionally restricted S5A stria vascularis Expression is at the apical cell junctions of marginal cells.
Specimen S5B: postnatal day 2 (more )
Note: Double labeled: green - Shroom2; red - Myo7a (assay MGI:5806148).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted S5B organ of corti , S5B mShrm2 Expression is in the auditory sensory epithelium.
Specimen S5B right: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted S5B mShrm2 cross section Expression is in inner and outer hair cells.
Specimen S5B P2: postnatal day 2 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted S5B P2 mShrm2 , S5B P2 +ZO1 Expression is at the apical hair cell surface.
Specimen S5B P14: postnatal day 14 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S5B P14 Expression is at the apical hair cell surface.
Specimen S5B P90: postnatal day 90 (more )
Note: Double labeled: green - Shroom2; red - F-actin.
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S5B P90 high power merge , S5B P90 high power , S5B P90 Expression is at the apical hair cell surface.
Specimen S5C left: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted S5C utricular macula Expression is in the hair cells at the apical junctional complex.
Specimen S5C right: postnatal day 2 (more )
Note: Double labeled: green - Shroom2; red - Tjp1 (assay MGI:5807100).
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted S5C mShrm2 + ZO1 , S5C mShrm2 Expression is in the hair cells at the apical junctional complex.
Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present
Specimen not shown adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: nasal epithelium Present Regionally restricted Expression is in the apical region of the epithelia.
TS28: testis Present Regionally restricted Expression is in the apical region of the epithelia.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory