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Gene Expression Data
Assay Details
Assay
Reference: J:229524 Robert T, et al., The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800403
Gene symbol: Dmc1
Gene name: DNA meiotic recombinase 1
Antibody: anti-Dmc1 (H-100; sc-22768)
Detection system: Secondary antibody
Results
Specimen S17A +/+ Leptotene: postnatal month 8 (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Ambiguous S17A_+/+ Leptotene Merge , S17A_+/+ Leptotene Dmc1
Specimen S17A +/+ Zygotene: postnatal month 8 (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Ambiguous S17A_+/+ Zygotene Merge , S17A_+/+ Zygotene Dmc1
Specimen S17A +/+ Pachytene: postnatal month 8 (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Ambiguous S17A_+/+ Pachytene Dmc1 , S17A_+/+ Pachytene Merge
Specimen S17A -/- Leptotene: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Weak S17A_-/- Leptotene Merge , S17A_-/- Leptotene Dmc1
Specimen S17A -/- Zygo. Like: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Weak S17A_-/- Zygo. Like Dmc1 , S17A_-/- Zygo. Like Merge
Specimen S17A -/- Zygo Like: postnatal month 8; Top6blem1Arte/Top6blem2Arte (more )
Note: Double labeled: green - Dmc1; red - Sycp3 (assay MGI:5800404). Meiotic nuclear spread from testis.
Structure Level Pattern Image Note
TS28: spermatocyte Weak S17A_-/- Zygo Like Dmc1 , S17A_-/- Zygo Like Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/22/2024
MGI 6.24 		The Jackson Laboratory