Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(CMV-AR*113Q)FMonk
Name:	transgene insertion F, Douglas Monks
MGI ID:	MGI:5790708
Synonyms:	CMV-stop-AR113Q
Transgene:	Tg(CMV-AR*113Q)FMonk  Location: unknown
Alliance:	Tg(CMV-AR*113Q)FMonk page

Strain of Origin:

(C57BL/6 x C3H)F2

Transgene Type:    Transgenic (Conditional ready, Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(CMV-AR*113Q)FMonk expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human AR (367) Ar  (MGI:88064) contains a polyglutamine expansion with 113 repeats.   Mutation details: The transgenic construct consists of CMV promoter sequences, a loxP-flanked neomycin-STOP cassette and a full length human androgen receptor (AR) cDNA containing a polyglutamine expansion with 113 repeats. (J:221668)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:221668 Ramzan F, et al., Distinct Etiological Roles for Myocytes and Motor Neurons in a Mouse Model of Kennedy's Disease/Spinobulbar Muscular Atrophy. J Neurosci. 2015 Apr 22;35(16):6444-51
All:	1 reference(s)