Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(UBC-Pou5f1,-EGFP)18Dann
Name:	transgene insertion 18, Christina Dann
MGI ID:	MGI:5790657
Synonyms:	cOct4
Transgene:	Tg(UBC-Pou5f1,-EGFP)18Dann  Location: unknown
Alliance:	Tg(UBC-Pou5f1,-EGFP)18Dann page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter) Mutation:    Insertion   Tg(UBC-Pou5f1,-EGFP)18Dann expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Pou5f1 (MGI:101893)   Mutation details: The transgenic construct contains (5' to 3') a human ubiquitin C (UB) gene promoter, a floxed STOP cassette (3 repeats of SV40 polyA stop sequence flanked by loxP sites), the mouse Pou5f1 coding sequence with a myc tag, T2A/furin ribosomal skip sequence, EGFP coding sequence, and a BGH poly(A) sequence. (J:236622)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:236622 Zheng Y, et al., Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice. Reproduction. 2016 Oct;152(4):363-77
All:	1 reference(s)