Gene Expression Data
Assay Details
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Assay
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Reference:
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J:25
Beermann F, et al., Expression of the mouse tyrosinase gene during embryonic development: recapitulation of the temporal regulation in transgenic mice. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2809-13
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5788720
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Gene symbol:
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Tyr
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Gene name:
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tyrosinase
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Probe:
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Tyr probe
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
1A:
embryonic day 10.5; Tyrc/ Tyrc
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: retina epithelium |
Present |
Regionally restricted |
1A
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Expressed in the pigmented epithelium.
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Specimen
1B:
embryonic day 10.5; Tyrc/ Tyrc
(more )
Specimen
1B:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: retina epithelium |
Present |
Regionally restricted |
1B
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Expressd in the pigmented epithelium.
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Specimen
1C:
embryonic day 12.5; Tyrc/ Tyrc
(more )
Specimen
1C:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1D:
embryonic day 14.5; Tyrc/ Tyrc
(more )
Specimen
1D:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1E:
embryonic day 16.5; Tyrc/ Tyrc
(more )
Specimen
1E:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2A:
embryonic day 16.5; Tyrc/ Tyrc
(more )
Specimen
2A:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2B:
embryonic day 17.5; Tyrc/ Tyrc
(more )
Specimen
2B:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: back skin |
Present |
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2B
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Increased expression.
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| TS25: hair follicle |
Present |
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2B
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Increased expression. Almost all hair follicles contain expressing melanocytes.
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Specimen
2C:
embryonic day 18.5; Tyrc/ Tyrc
(more )
Specimen
2C:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2D:
embryonic day 16.5; Tyrc/ Tyrc
(more )
Specimen
2D:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2E:
embryonic day 17.5; Tyrc/ Tyrc
(more )
Specimen
2E:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: back skin |
Present |
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2E
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Increased expression.
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| TS25: hair follicle |
Present |
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2E
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Increased expression. Almost all hair follicles contain expressing melanocytes.
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Specimen
2F:
embryonic day 18.5; Tyrc/ Tyrc
(more )
Specimen
2F:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown:
embryonic day 9.5; Tyrc/ Tyrc
(more )
Specimen
not shown:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: eye |
Absent |
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Specimen
not shown:
embryonic day 12.5-13.5; Tyrc/ Tyrc
(more )
Specimen
not shown:
(close )
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Genetic Background:
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NMRI/Han
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Mutant Allele(s):
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Tyrc/Tyrc
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Age:
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embryonic day 12.5-13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: eyelid |
Present |
Single cells |
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Expressed in isolated melanoblasts/melanocytes.
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Analysis Tools