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Gt(ROSA)26Sortm1(CAG-NGFR*)Mtac
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-NGFR*)Mtac
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Makoto Tachibana
MGI ID: MGI:5788502
Synonyms: R26-CAG-LoxP-hCD271
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-NGFR*)Mtac page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:233557
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe targeting construct inserted into the locus a puromycin resistance cassette, CAG promoter, floxed polyadenylation sequence, a truncated human sequence lacking the cytoplasmic portion of the protein and a polyadenylation sequence. (J:233557)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:233557 Kuroki S, et al., Development of a general-purpose method for cell purification using Cre/loxP-mediated recombination. Genesis. 2015 Jun;53(6):387-93
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory