Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Atp13a2tm1.1Wtd
Name:	ATPase type 13A2; targeted mutation 1.1, William T Dauer
MGI ID:	MGI:5779523
Synonyms:	Apt13a2-flx
Gene:	Atp13a2  Location: Chr4:140714184-140734641 bp, + strand  Genetic Position: Chr4, 73.29 cM
Alliance:	Atp13a2tm1.1Wtd page

Germline Transmission:	Earliest citation of germline transmission: J:221680
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6 x 129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 2 followed by an FRT-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:221680)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp13a2 Mutation:	60 strains or lines available

Original:	J:221680 Kett LR, et al., alpha-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015 Apr 8;35(14):5724-42
All:	2 reference(s)