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Gene Expression Data
Assay Details
Assay
Reference: J:65596 Voss AK, et al., Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos. Development. 2000 Dec;127(24):5449-61
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5775401
Gene symbol: Taf8
Gene name: TATA-box binding protein associated factor 8
Reporter: lacZ
Direct Detection
Results
Specimen 3A het: embryonic day 2.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS3: compacted morula Weak Widespread 3A Staining is seen in all blastomeres.

Specimen 3A hom: embryonic day 2.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8Gt(pGT1.8geo)9Pgr (more )
Structure Level Pattern Image Note
TS3: compacted morula Weak Widespread 3A Staining is seen in all blastomeres. Staining in 21% of the embryos from the cross have double intensity; these are presumed to be the homozygotes.

Specimen 5A het: embryonic day 3.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 5A Staining in the inner cell mass is more intense than in the trophectoderm.
TS4: trophectoderm Present 5A Staining in the inner cell mass is more intense than in the trophectoderm.

Specimen 5a hom: embryonic day 3.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8Gt(pGT1.8geo)9Pgr (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 5A Staining in the inner cell mass is more intense than in the trophectoderm. Staining in 21% of the embryos from the cross have double intensity; these are presumed to be the homozygotes.
TS4: trophectoderm Present 5A Staining in the inner cell mass is more intense than in the trophectoderm. Staining in 21% of the embryos from the cross have double intensity; these are presumed to be the homozygotes.

Specimen not shown: embryonic day 6.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS9: embryo Weak Ubiquitous Staining is observed in all tissues.

Specimen not shown: embryonic day 7.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS11: embryo Weak Ubiquitous Staining is observed in all tissues.

Specimen 3C: embryonic day 8.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS13: embryo Weak Ubiquitous 3C Staining is observed in all tissues.

Specimen 3G: embryonic day 11.5; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS19: embryo Weak Widespread 3G
TS19: heart Present 3G Staining in the heart is more intense than in other tissues.

Specimen not shown: postnatal adult; Taf8Gt(pGT1.8geo)9Pgr/Taf8+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Staining in the brain is seen primarily in the hippocampus. It is not seen in tissues outside the brain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory