Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(CAG-EGFP,-Tnf)1Kul
Name:	transgene insertion 1, Ashok B Kulkarni
MGI ID:	MGI:5771790
Synonyms:	TNF-alphaglo
Transgene:	Tg(CAG-EGFP,-Tnf)1Kul  Location: unknown
Alliance:	Tg(CAG-EGFP,-Tnf)1Kul page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter) Mutation:    Insertion   Tg(CAG-EGFP,-Tnf)1Kul expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Tnf (MGI:104798)   Mutation details: The transgene was designed with (from 5' to 3') a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), a loxP-flanked fusion protein containing an enhanced green fluorescent protein sequence (EGFP), and a polyadenylation (pA) signal, a mouse tumor necrosis factor (Tnf) cDNA followed by a two pA signals. (J:231511)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:231511 Hall BE, et al., Conditional TNF-alpha Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis. J Dent Res. 2016 Feb;95(2):188-95
All:	1 reference(s)