Gene Expression Data
Assay Details
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Assay
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Reference:
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J:61486
Littlewood Evans A, et al., Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5755674
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Gene symbol:
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Fn1
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Gene name:
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fibronectin 1
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Antibody:
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anti-Fibronectin
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Detection system:
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Secondary antibody coupled to rhodamine
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Results
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Specimen
5a +/-:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: utricle epithelium |
Present |
Regionally restricted |
5a FN +/-
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Expression is at the apical surface of the hair cell layer.
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Specimen
5a -/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8tm1Lfr
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
5b +/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule epithelium |
Present |
Regionally restricted |
5b FN +/-
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Expression is at the apical surface of the hair cell layer.
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Specimen
5b -/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8tm1Lfr
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule epithelium |
Present |
Regionally restricted |
5b FN -/-
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Expression is perturbed at the apical surface of the hair cell layer.
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Specimen
5c +/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
5c FN +/-
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Expression is at the basement membrane and at the apical surface of the hair cells.
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Specimen
5c -/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8tm1Lfr
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
5c FN -/-
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Expression in this mutant is the same as in wild-type.
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Itga8tm1Lfr/Itga8tm1Lfr
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: crista ampullaris |
Present |
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Expression in this mutant is the same as in wild-type.
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Analysis Tools
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