Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Akap11tm1.1Jsco
Name:	A kinase anchor protein 11; targeted mutation 1.1, John D Scott
MGI ID:	MGI:5751850
Synonyms:	Akap11lox
Gene:	Akap11  Location: Chr14:78729686-78774248 bp, - strand  Genetic Position: Chr14, 41.46 cM
Alliance:	Akap11tm1.1Jsco page

Germline Transmission:	Earliest citation of germline transmission: J:234905
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site and FRT-flanked neomycin cassette are introduced into intron 5 of the gene, a second loxP site is placed in intron 7. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 6 and 7 flanked by loxP sites. (J:234905)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akap11 Mutation:	65 strains or lines available

Original:	J:234905 Whiting JL, et al., AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4328-37
All:	2 reference(s)