Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pld1tm1.2Gdp
Name:	phospholipase D1; targeted mutation 1.2, Gilbert Di Paolo
MGI ID:	MGI:5751724
Synonyms:	Pld1Flox
Gene:	Pld1  Location: Chr3:27992844-28187511 bp, + strand  Genetic Position: Chr3, 11.15 cM
Alliance:	Pld1tm1.2Gdp page

Germline Transmission:	Earliest citation of germline transmission: J:207283
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6 x 129/SvJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 13. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 14. FLP-mediated recombination removed the neo cassette. (J:207283)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pld1 Mutation:	64 strains or lines available

Original:	J:207283 Dall'Armi C, et al., The phospholipase D1 pathway modulates macroautophagy. Nat Commun. 2010;1:142
All:	2 reference(s)