Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Pax8-YFP)1Amc
Name:	transgene insertion 1, Andrew P McMahon
MGI ID:	MGI:5750065
Synonyms:	Pax8YFPtg
Transgene:	Tg(Pax8-YFP)1Amc  Location: unknown
Alliance:	Tg(Pax8-YFP)1Amc page

Strain of Origin:

CD-1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Tg(Pax8-YFP)1Amc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Pax8 (MGI:97492)   Mutation details: The 166 kb C57BL/6J mouse bacterial artificial chromosome (BAC) from the RPCI23 library containing the entire Pax8 locus (and other genes) was modified by targeting a yellow fluorescent protein (YFP) coding sequence into the ATG start site of Pax8. This inserted a YFP fusion protein coding sequence, SV40 polyA signal, and a FRT-flanked Kanamycin resistance gene cassette. No other genes on the BAC were modified or deleted. Flp-mediated recombination removed the Kanamycin cassette. The BAC clone backbone vector (pBACe3.6), which contains the chloramphenicol resistance (CmR) gene, was not removed prior to microinjection and thus is retained in the transgenic animals. (J:264384)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:264384 Ramalingam H, et al., Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 Aug 1;440(1):13-21
All:	1 reference(s)