Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Afap1tm1.1Ycho
Name:	actin filament associated protein 1; targeted mutation 1.1, Youngjin Cho
MGI ID:	MGI:5707262
Synonyms:	Afapfl
Gene:	Afap1  Location: Chr5:36050713-36161267 bp, + strand  Genetic Position: Chr5, 19.02 cM, cytoband B1
Alliance:	Afap1tm1.1Ycho page

Germline Transmission:	Earliest citation of germline transmission: J:221250
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: Exon 5 was floxed. Flp-mediated recombination removed the FRT-flanked selection cassette inserted downstream of exon 5. (J:221250)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Afap1 Mutation:	59 strains or lines available

Original:	J:221250 Cunnick JM, et al., Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 2015 May 14;34(20):2640-9
All:	1 reference(s)